Figure 5From: SIRT1/PARP1 crosstalk: connecting DNA damage and metabolismInteractions between SIRT1 and transcription factors c-MYC and E2F1. Solid lines between SIRT1 and c-MYC indicated are interactions from Yuan, Minter-Dykhouse et al. 2009 forming a negative feedback loop, while dashed lines are findings related to SIRT1 and c-MYC from Menssen, Hydbring et al. 2012.Back to article page