Localization of H4K16ac peaks in the HEK293 genome. (A) Genome-wide distribution of H4K16ac peaks. H4K14ac peak distribution was categorized as within exon, intron, coding and other genomic locations as described. Each bar represents the percentage of peaks in each category. (B) Correlation of H4K16ac peaks and gene density in human chromosome 1. The bar graph for H4K16ac density and the gene density map of human chromosome 1 are aligned. Although these two diagrams are well correlated (I and II), some regions show differences (III and IV). (C) Gene ontology for the genes enriched by H4K16ac ChIP. A total of 3,538 genes identified as H4K16ac positive genes are subjected to gene ontology analysis.