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Figure 7 | Genome Integrity

Figure 7

From: Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin

Figure 7

B-NHEJ kinetics in TSA-treated exponentially growing M059K cells incubated for repair in the presence of 20 μM wortmannin. Other details are as shown in Figure 5 for Lig4-/- MEFs. M059K cells were subjected to 20 μM wortmannin treatment 40 min before the beginning of the experiment in order to inhibit D-NHEJ and allow thus analysis of B-NHEJ activity. Data shown are the means and standard errors of four determinations in one experiment.

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Genome Integrity

ISSN: 2041-9414