Table 1 Percent of crypts which showed high expression of Pms2, Ercc1 or Ku86
From: Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer
Patient designation C = cancer A = adenoma | Total crypts evaluated (# of tissue samples) | % Pms2 high in each tissue section | % Ercc1 high in each tissue section | % Ku86 high in each tissue section |
|---|---|---|---|---|
C1 | 958 (6) | 22,15,42,1,22,13 | 40,18,19,29,10,16 | 98,100,93,96,99,100 |
C2 | 921 (5) | 32,31,9,1,17,- | 26,13,25,10,13,- | 99,98,100,99,99,- |
C3 | 968 (6) | 33,87,5,1,1,0 | 91,5,92,21,11,97 | N.D. |
C4 | 2,411 (6) | 1,4,0,0,1,8 | 5,11,9,8,11,18 | N.D. |
C5 | 448 (4) | -,0,0,0,-,0 | -,0,4,12,-,15 | N.D. |
C6 | 1,801 (5) | 7,1,32,-,11,0 | 38,87,18,-,1,6 | N.D. |
C7 | 2,844 (6) | 2,58,43,2,2,3 | -,52,45,48,70,52 | N.D. |
C8 | 1,742 (6) | 1,3,1,0,1,2 | 4,5,10,6,13,8 | 97,97,97,100,99,99 |
A1 | 433 (2) | 14,19 | 7,3 | 99,- |
A2 | 195 (2) | 2,16 | 16,20 | 79,75 |
A3 | 90 (2) | 0,0 | 2,27 | 100,- |
A4 | 112 (2) | 0,0 | 24,14 | 92,87 |
A5 | 129 (2) | 0,0 | 10,24 | 64,98 |
A6 | 72 (2) | 0,3 | 15,18 | 89,89 |
A7 | 255 (2) | 5,9 | 37,29 | 94,48 |
A8 | 203 (2) | 0,0 | 15,29 | 100,95 |