Skip to main content

Table 1 Percent of crypts which showed high expression of Pms2, Ercc1 or Ku86

From: Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer

Patient designation C = cancer A = adenoma Total crypts evaluated (# of tissue samples) % Pms2 high in each tissue section % Ercc1 high in each tissue section % Ku86 high in each tissue section
C1 958 (6) 22,15,42,1,22,13 40,18,19,29,10,16 98,100,93,96,99,100
C2 921 (5) 32,31,9,1,17,- 26,13,25,10,13,- 99,98,100,99,99,-
C3 968 (6) 33,87,5,1,1,0 91,5,92,21,11,97 N.D.
C4 2,411 (6) 1,4,0,0,1,8 5,11,9,8,11,18 N.D.
C5 448 (4) -,0,0,0,-,0 -,0,4,12,-,15 N.D.
C6 1,801 (5) 7,1,32,-,11,0 38,87,18,-,1,6 N.D.
C7 2,844 (6) 2,58,43,2,2,3 -,52,45,48,70,52 N.D.
C8 1,742 (6) 1,3,1,0,1,2 4,5,10,6,13,8 97,97,97,100,99,99
A1 433 (2) 14,19 7,3 99,-
A2 195 (2) 2,16 16,20 79,75
A3 90 (2) 0,0 2,27 100,-
A4 112 (2) 0,0 24,14 92,87
A5 129 (2) 0,0 10,24 64,98
A6 72 (2) 0,3 15,18 89,89
A7 255 (2) 5,9 37,29 94,48
A8 203 (2) 0,0 15,29 100,95
  1. Percent of crypts with high expression in cancer resections are shown in order, from left to right, for 10, 3 or 1 cm proximal to and for 1, 3 or 10 cm distal to the cancer. Percent of crypts with high expression in tubulovillus adenoma resections are shown in order 10 cm and 1 cm from the tumor. A dash indicates that the tissue sample was not available for immunostaining. N.D. indicates Not Done