Figure 6
From: Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer
Sequential tissue sections with discordant expression of Pms2, Ercc1 and Xpf. These crypts are from the biopsy of a 71 year old female patient who had a 1 cm adenocarcinoma. While Pms2 and Xpf have reduced expression in this tissue area, Ercc1 has high expression. In this mucosal area, one crypt is apparently fissioning into 3 crypts. Images taken at 200×.