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Table 2 Gene expression pattern in DNA damage pathway.

From: Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells

IMR-90 U251
Gene Genbank ID Fold change Gene Genbank ID Fold change
GADD45G NM_006705 6.12 ABL1 NM_005157 1.69
BRCA1 NM_007294 -0.44 GML NM_002066 0.52
ABL1 NM_005157 -0.39 BRCA1 NM_007294 1.89
GML NM_002066 -0.43 ZAK NM_016653 2.54
XRCC5 NM_021141 -0.34 ATR NM_001184 0.21
MSH2 NM_000251 -0.28 XRCC5 NM_021141 0.59
RAD51C NM_058216 -0.74 XPA NM_000380 0.91
ERCC3 NM_000122 -0.73 TREX1 NM_016381 0.51
OGG1 NM_002542 -0.45 PMS1 NM_000534 0.64
XRCC1 NM_006297 -0.31 CCNU NM_021147 1.52
MBD4 NM_003925 -0.59 APEX2 NM_014481 0.29
APEX1 NM_080649 -0.67 ATM NM_000051 1.98
MUTYH NM_012222 -0.49 TP53 NM_000546 -0.28
PMS1 NM_000534 -0.64 FEN1 NM_004111 -0.51
SUMO1 NM_003352 -0.69 RAD51C NM_058216 -0.24
ATM NM_000051 -0.50 PCNA NM_182649 -0.46
CCNH NM_001239 -0.77 RPA1 NM_002945 -0.60
IGHMBP2 NM_002180 -0.50    
LIG3 NM_002311 -0.48    
APEX2 NM_014481 -0.29    
PCNA NM_182649 -0.69    
RPA1 NM_002945 -0.53    
  1. Regulation of DNA damage response genes in silver nanoparticle treated IMR 90 and U251cells. Fold change is calculated as indicated in table 1.