Genome Integrity

Table 2 Gene expression pattern in DNA damage pathway.

From: Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells

IMR-90			U251
Gene	Genbank ID	Fold change	Gene	Genbank ID	Fold change
GADD45G	NM_006705	6.12	ABL1	NM_005157	1.69
BRCA1	NM_007294	-0.44	GML	NM_002066	0.52
ABL1	NM_005157	-0.39	BRCA1	NM_007294	1.89
GML	NM_002066	-0.43	ZAK	NM_016653	2.54
XRCC5	NM_021141	-0.34	ATR	NM_001184	0.21
MSH2	NM_000251	-0.28	XRCC5	NM_021141	0.59
RAD51C	NM_058216	-0.74	XPA	NM_000380	0.91
ERCC3	NM_000122	-0.73	TREX1	NM_016381	0.51
OGG1	NM_002542	-0.45	PMS1	NM_000534	0.64
XRCC1	NM_006297	-0.31	CCNU	NM_021147	1.52
MBD4	NM_003925	-0.59	APEX2	NM_014481	0.29
APEX1	NM_080649	-0.67	ATM	NM_000051	1.98
MUTYH	NM_012222	-0.49	TP53	NM_000546	-0.28
PMS1	NM_000534	-0.64	FEN1	NM_004111	-0.51
SUMO1	NM_003352	-0.69	RAD51C	NM_058216	-0.24
ATM	NM_000051	-0.50	PCNA	NM_182649	-0.46
CCNH	NM_001239	-0.77	RPA1	NM_002945	-0.60
IGHMBP2	NM_002180	-0.50
LIG3	NM_002311	-0.48
APEX2	NM_014481	-0.29
PCNA	NM_182649	-0.69
RPA1	NM_002945	-0.53

Regulation of DNA damage response genes in silver nanoparticle treated IMR 90 and U251cells. Fold change is calculated as indicated in table 1.

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