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Figure 3 | Genome Integrity

Figure 3

From: Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells

Figure 3

Altered gene expression profile in Ag-np treated cells. (a) Quantitative analysis of γH2AX foci showed more double strand DNA damage induced in U251 cells compared IMR-90 cells. Untreated U251 cells (b) showing minimal foci, (c) cells exposed to 25 μg/mL of Ag-np-3 (d) 50 μg/mL (e) 100 μg/mL and (f) 10 μM H2O2, showing multiple foci. (g) Untreated IMR90 cells shows no foci whereas, exposure with (h) 25 μg/mL of Ag-np-3 (i) 50 μg/mL (j) 100 μg/mL and (k) 10 μM H2O2, shows multiple foci.

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