Figure 4From: Resolution of complex ends by non-homologous end joining - better to be lucky than good?End cleaning. Ligation-blocking damage can be excised by enzymes (e.g. APTX, PNKP, APLF, Tdps, Ku; purple and green proteins) that recognize and remove specific end structures (i). Family X polymerases (light blue oval) can replace the excised DNA (ii) prior to ligation (iii).Back to article page