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Figure 6 | Genome Integrity

Figure 6

From: Development and validation of 'AutoRIF': software for the automated analysis of radiation-induced foci

Figure 6

Effects of RIF filtering steps. Pre-laplacian, laplacian and post-laplacian filtering effects on an image of a single nucleus with 53BP1 foci. The optimal filtering combination for this nucleus would be 3 pre-filtering steps, medium sensitivity laplacian filter and 3 post-laplacian filtering steps. ~10% of nuclei are batch tested (covering test and sham slides) to identify the optimal combination of filters to be used for each experiment.

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