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Figure 6 | Genome Integrity

Figure 6

From: Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner

Figure 6

FANCD2 deficiency leads to formation of extrachromosomal telomeric structures. 2D Southern blot analyses of telomeric DNA signals of PD20 (A) and PD20 corrected cells (B). Scheme representing different types of extrachromosomal DNA resolved on two dimensional gel electrophoresis (C). Densitometric analyses of linear and circular extrachromosomal telomeric structures (D).

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