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Figure 6 | Genome Integrity

Figure 6

From: Localization of an hTERTrepressor region on human chromosome 3p21.3 using chromosome engineering

Figure 6

Identification of an hTERT repressor locus on human chromosome 3p21.3 Twenty-four STS markers on 3p examined were shown. Open circles, absence of tested loci in transferred human chromosome. Closed circles, presence of tested loci in transferred human chromosome. STS markers in bold were used in Figure 2b as well. Note that 7-Mb interval between D3S3597 and D3S1573 on 3p21.3 contains the effect of endogenous hTERT repression into RCC23-exohTERT cells. Interstitial deletion of transferred chromosome was observed on D3S1573 and D3S3561 loci in A9(#3delp2-pter) clone, and D3S1573 locus in A9(#3del21.3-pter) clone.

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