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Figure 5 | Genome Integrity

Figure 5

From: Localization of an hTERTrepressor region on human chromosome 3p21.3 using chromosome engineering

Figure 5

hTERT repression effect on #3delp24-pter and #3del22-pter, but not #3delp21.3-pter Two clones of each RCC23-exohTERT microcell hybrids were examined by RT-PCR. GAPDH was used as an internal control. RT-PCR was performed with (+) or without (-) reverse transcriptase (RT). Note that the RCC23-exohTERT microcell hybrid containing an intact (#3) or the truncated human chromosome 3, #3delp24-pter or #3delp22-pter has no expression of endogenous hTERT gene (endohTERT).

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