Figure 2
From: Localization of an hTERTrepressor region on human chromosome 3p21.3 using chromosome engineering
Construction of truncated chromosome 3 in DT40 cells by telomere seeding. (A) Targeting strategy of generating truncated chromosome. (B) Summary of PCR analyses on truncated chromosomes in DT40 cells. Twenty STS markers on chromosome 3 examined were shown. Solid circles and open circles represent presence and absence of truncated allele at tested loci in DT40 cells, respectively.