Table 1 Functional categorisation of differentially expressed genes in wild type, mTERC -/- and PARP-1-/- MEFs following arsenite treatment.
Gene Name | GeneBank ID | mTERC-/- | PARP-1-/- |
|---|---|---|---|
Cell death | Â | Â | Â |
Aifm2 | AK017403 | 6.50 | 4.50 |
Bcl2l11 | BB667581 | 3.47 | 2.22 |
Siva | AF033112 | 3.37 | 1.24 |
Sphk1 | AF068749 | 3.22 | 3.35 |
Pik3r1 | M60651 | 1.24 | -2.45 |
Birc1f | AI451585 | -1.58 | -2.15 |
IAP1 | NM_007464 | -2.55 | -1.72 |
FLG | M33760 | -3.13 | -1.65 |
Casp9 | BB815299 | -3.78 | 1.68 |
Faim-L | NM_011810 | -4.24 | -1.38 |
Fam | NM_007983 | -8.56 | -1.33 |
Birc6 | BM228823 | -9.20 | -2.41 |
Dad1 | BI966630 | -9.29 | -1.67 |
Cycs | NM_007808 | -9.47 | -2.83 |
Stk17b | AI661948 | -9.94 | 1.01 |
Il-6 | NM_031168 | -12.48 | -8.72 |
Bip | NM_022310 | -20.04 | -3.15 |
DNA damage response | Â | Â | Â |
Brca2 | NM_009765 | -1.64 | -2.09 |
Xrn2 | NM_011917 | -1.82 | -1.01 |
H2afx | NM_010436 | -2.04 | -2.03 |
Ddb2 | AI131584 | -2.07 | 1.16 |
Rad51ap1 | BC003738 | -2.31 | -2.59 |
Ercc5 | BM198879 | -2.32 | -1.33 |
Gadd45a | NM_007836 | -2.57 | -1.67 |
Mlh1 | NM_026810 | -2.82 | -1.46 |
Msh6 | U42190 | -2.94 | -1.56 |
Chek2 | NM_016681 | -3.09 | -1.72 |
1110013J05Rik | NM_025392 | -3.17 | -2.17 |
Lig4 | AW545311 | -4.01 | -1.95 |
Sod1 | BC002066 | -6.15 | -1.81 |
Mapk14 | BC012235 | -7.63 | -2.63 |
Telomere homeostasis | Â | Â | Â |
Smg6 | BC006644 | 3.18 | 6.26 |
Adprt1 | BB767586 | 2.49 | -4.06 |
Terf2 | BI439979 | 2.01 | -2.23 |
Hspa1b | M12573 | 1.28 | 1.43 |
Blm | NM_007550 | 1.02 | -2.77 |
DNA-PK | D87521 | -1.98 | -3.18 |