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Table 1 Functional categorisation of differentially expressed genes in wild type, mTERC -/- and PARP-1-/- MEFs following arsenite treatment.

From: Inhibition of poly (ADP-Ribose) polymerase-1 in telomerase deficient mouse embryonic fibroblasts increases arsenite-induced genome instability

Gene Name GeneBank ID mTERC-/- PARP-1-/-
Cell death    
Aifm2 AK017403 6.50 4.50
Bcl2l11 BB667581 3.47 2.22
Siva AF033112 3.37 1.24
Sphk1 AF068749 3.22 3.35
Pik3r1 M60651 1.24 -2.45
Birc1f AI451585 -1.58 -2.15
IAP1 NM_007464 -2.55 -1.72
FLG M33760 -3.13 -1.65
Casp9 BB815299 -3.78 1.68
Faim-L NM_011810 -4.24 -1.38
Fam NM_007983 -8.56 -1.33
Birc6 BM228823 -9.20 -2.41
Dad1 BI966630 -9.29 -1.67
Cycs NM_007808 -9.47 -2.83
Stk17b AI661948 -9.94 1.01
Il-6 NM_031168 -12.48 -8.72
Bip NM_022310 -20.04 -3.15
DNA damage response    
Brca2 NM_009765 -1.64 -2.09
Xrn2 NM_011917 -1.82 -1.01
H2afx NM_010436 -2.04 -2.03
Ddb2 AI131584 -2.07 1.16
Rad51ap1 BC003738 -2.31 -2.59
Ercc5 BM198879 -2.32 -1.33
Gadd45a NM_007836 -2.57 -1.67
Mlh1 NM_026810 -2.82 -1.46
Msh6 U42190 -2.94 -1.56
Chek2 NM_016681 -3.09 -1.72
1110013J05Rik NM_025392 -3.17 -2.17
Lig4 AW545311 -4.01 -1.95
Sod1 BC002066 -6.15 -1.81
Mapk14 BC012235 -7.63 -2.63
Telomere homeostasis    
Smg6 BC006644 3.18 6.26
Adprt1 BB767586 2.49 -4.06
Terf2 BI439979 2.01 -2.23
Hspa1b M12573 1.28 1.43
Blm NM_007550 1.02 -2.77
DNA-PK D87521 -1.98 -3.18
  1. Expression profile of selected genes, which were differentially expressed to a fold change of 2.0 or more in one of the treatments are given. Data indicate the fold increase (positive values) or decrease (negative values) in treated samples compared to corresponding normal controls.