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Figure 6 | Genome Integrity

Figure 6

From: Requirement of ATM-dependent pathway for the repair of a subset of DNA double strand breaks created by restriction endonucleases

Figure 6

Effect of ATM inhibition on DNA damage foci repair Synchronized normal human diploid cells in G1 were electroporated with 100 U of various restriction endonucleases with or without 20 μM KU55933. The cells were incubated for the time indicated before fixation. At least 1000 nuclei were examined. C; mock-treated control cells without restriction endonucleases. Black bars and dark gray bars represent cells with Type IV and Type III nuclei, respectively.

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