Figure 2
Cell cycle profiles of A. Normal-L, B. XPA-L, C. XPB-L, and D. XPD-L lymphoblastoid cells following H 2 O 2 treatment. PI: Propidium iodide, indicating amount of DNA stained per cell. The top profile of panel A depicts an illustration of the distribution of cells in each phase of the cell cycle (sub G1: apoptotic cells; G1: G1-phase cells; S: S-phase cells; G2/M: G2/M-phase cells). E. Percentage of sub-G1 population. F. Percentage of G2/M population in XPA-L cells. #p < 0.05; ##p < 0.01; ###p < 0.001 compared to untreated counterparts. *p < 0.05; ***p < 0.001 compared to Normal-L. Data is representative of at least three independent experiments.