Figure 4

Effect of MTHFR C677C and T677T genotype on DNA damage, homocysteine and cell growth. The differential effects of the MTHFR C677T genotype on micronuclei, nuclear buds, homocysteine and cell growth. It is evident from the results of this study that homozygous carriers of the T allele tended to have higher levels of micronuclei, homocysteine and cell growth and lower frequencies of nuclear buds relative to homozygous carriers of the common C allele. For more details refer to Kimura et al 2004 [28]. * P < 0.05 relative to corresponding CC